| Alessia Cara | Best Dance Recording, Best Rap Song (2) |
| Anne-Marie | Best Dance Recording (1) |
| Bebe Rexha | Best Duo/Group Performance (1) |
| Camila Cabello | Best Duo/Group Performance, Video Of the Year, Record Of The Year, Best New Artist (4) |
| Cardi B | Best Rap Artist, Best Rap Song, Artist Of The Year, Best New Artist (4) |
| Clean Bandit | Best Dance Recording (1) |
| Demi Lovato | Best Solo Pop Performance, Best Pop Vocal Album, Album Of The Year (3) |
| Drake | Best Rap Song, Best Rap Artist (2) |
| Fifth Harmony | Best Duo/Group (1) |
| Iggy Azalea | Best Rap Artist, Best Dance Recording (2) |
| Julia Michaels | Best New Artist (1) |
| Katy Perry | Best Duo Group Performance, Video Of The Year (X2), Album of The Year, Artist of The Year (5) |
| Kelly Clarkson | Best Solo Pop Perfomance, Best Pop Vocal Album, Song Of The Year (3) |
| Khalid | Best Rap Song, Best New Artist (2) |
| Kendrick Lamar | Best Rap Song, Best Rap Artist, Artist of The Year, Song of The Year (4) |
| Kesha | Song Of The Year, Best Pop Performance, Best Pop Vocal Album (3) |
| Lady Gaga | Best Solo Pop Performance, Best Pop Vocal Album, Album of the Year, Record of the Year, Best Dance Recording, Song of the Year (6) |
| Lil Wayne | Best Rap Song (1) |
| Little Mix | Best Duo/Group (1) |
| Logic | Best Rap Song (1) |
| Lorde | Best Solo Pop Performance, Best Pop Vocal Album, Album of the Year (3) |
| Imagine Dragons | Best Duo/Group (1) |
| Niall Horan | Artist of The Year (1) |
| Nicki Minaj | Best Rap Song, Best Rap Artist (2) |
| Kygo | Best Dance Recording (1) |
| Portugal. The Man | Best Duo / Pop Group performance (1) |
| Sean Paul | Best Dance Recording (1) |
| Selena Gomez | Best Solo Pop Performance, Record of the Year, Best Dance Recording, Artist of the Year (4) |
| The Chainsmokers | Best Duo/Group (1) |
| Taylor Swift | Artist of the Year, Song of the Year, Best Duo/Group Performance, Video of the Year, Album of the Year, Record of the Year (6) |
| Twenty One Pilots | Best Duo/Group (1) |
| Dua Lipa | Best New Artist (1) |
| Zedd | Best Dance Recording (1) |
| Zayn | Best Duo/Group Performance (1) |
